Welcome To Project Main Street

Until there is a Cure for ALS there is Care


Project Main Street is a New York based 501c3 dedicated to providing financial grants to individuals living with ALS. Project Main Street has raised more than $3 million since our 2006 inception and distributes hundreds of grants per year. These unrestricted funds can contribute to the cost of home healthcare, medical and insurance expenses and home modifications. Named after Main Street in our hometown of Roosevelt Island, New York City, we truly believe in neighbors helping neighbors.